TB-Profiler result

Run: ERR11081490
Summary

Run ID: ERR11081490

Sample name:

Date: 08-04-2023 23:52:51

Number of reads: 3207265

Percentage reads mapped: 99.69

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.23
rpoB 761881 p.Ala692Val missense_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417298 p.Gly17Glu missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169041 c.1572G>A synonymous_variant 0.44
PPE35 2169044 c.1569G>C synonymous_variant 0.45
PPE35 2169047 p.Ile522Val missense_variant 0.36
PPE35 2169053 c.1560T>C synonymous_variant 1.0
PPE35 2169056 c.1557A>G synonymous_variant 0.36
PPE35 2169059 c.1554G>A synonymous_variant 0.64
PPE35 2169063 p.Met517Thr missense_variant 1.0
PPE35 2169065 p.Ala516Ile missense_variant 0.64
PPE35 2169068 c.1545G>T synonymous_variant 0.64
PPE35 2169071 c.1542A>G synonymous_variant 0.26
PPE35 2170065 p.Ala183Gly missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.16
pepQ 2860159 p.Ala87Gly missense_variant 0.11
fbiD 3339734 p.Ala206Gly missense_variant 0.86
fbiD 3339746 p.Ala210Gly missense_variant 0.45
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3474213 p.Lys69Asn missense_variant 0.13
rpoA 3878590 c.-84delC upstream_gene_variant 0.2
rpoA 3878641 c.-134C>G upstream_gene_variant 0.33
embC 4240409 p.Pro183Ala missense_variant 0.21
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246277 c.-237G>A upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.26
embB 4248324 p.Ala604Gly missense_variant 0.22
ethA 4328293 c.-820C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407945 c.258C>T synonymous_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0