TB-Profiler result

Run: ERR11081527

Summary

Run ID: ERR11081527

Sample name:

Date: 09-04-2023 01:30:20

Number of reads: 3804435

Percentage reads mapped: 99.78

Strain: lineage4.8

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.22
mshA 576482 p.Val379Leu missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
embR 1417131 p.His73Tyr missense_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.99
folC 2747556 p.Thr15Ala missense_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.17
ald 3087899 c.1080G>C synonymous_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.25
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3236c 3612574 c.543G>A synonymous_variant 1.0
rpoA 3878618 c.-111A>C upstream_gene_variant 0.22
rpoA 3878637 c.-130G>C upstream_gene_variant 0.12
rpoA 3878641 c.-134C>G upstream_gene_variant 0.18
clpC1 4038704 c.2001T>C synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244943 p.Ala571Thr missense_variant 0.5
embB 4246584 p.Arg24Pro missense_variant 0.46
embB 4248324 p.Ala604Gly missense_variant 0.18
whiB6 4338460 p.Met21Arg missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0