TB-Profiler result

Run: ERR11082456
Summary

Run ID: ERR11082456

Sample name:

Date: 10-04-2023 17:00:00

Number of reads: 4898878

Percentage reads mapped: 99.68

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6364 p.Leu375Phe missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.29
mshA 576482 p.Val379Leu missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1673841 c.-361A>G upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918091 p.Ala51Glu missense_variant 1.0
PPE35 2168458 p.Val719Ile missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518852 p.Met246Ile missense_variant 1.0
ald 3086987 p.Gln56His missense_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.29
rpoA 3878630 c.-123G>C upstream_gene_variant 0.13
rpoA 3878637 c.-130G>C upstream_gene_variant 0.19
rpoA 3878641 c.-134C>G upstream_gene_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243081 c.-152T>G upstream_gene_variant 1.0
embB 4246529 p.Ser6Arg missense_variant 0.21
embB 4246584 p.Arg24Pro missense_variant 0.37
embB 4248324 p.Ala604Gly missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0