TB-Profiler result

Run: ERR11082976
Summary

Run ID: ERR11082976

Sample name:

Date: 11-04-2023 15:28:25

Number of reads: 4558245

Percentage reads mapped: 99.56

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.99
gyrA 7916 c.615G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.21
ccsA 620478 c.588C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472321 n.477dupT non_coding_transcript_exon_variant 1.0
fabG1 1673213 c.-227A>G upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyX 3067559 c.387C>T synonymous_variant 0.99
thyA 3074477 c.-6T>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.27
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612234 c.883C>T synonymous_variant 1.0
Rv3236c 3612494 p.Arg208Gln missense_variant 1.0
fbiA 3641072 p.Arg177His missense_variant 1.0
rpoA 3878613 c.-106A>C upstream_gene_variant 0.3
rpoA 3878637 c.-130G>C upstream_gene_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.36
whiB6 4338595 c.-75delG upstream_gene_variant 1.0