Run ID: ERR1213918
Sample name:
Date: 2024-03-26T17:57:50.352208
Number of reads: 1862677
Percentage reads mapped: 99.02
Median coverage: 10.0
Strain: lineage4.6.2
Spoligotype:
Drug-resistance: Sensitive
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.6 | Euro-American | None | 0.83 |
lineage4.6.2 | Euro-American | RD726 | 0.85 |
lineage4 | Euro-American | None | 0.99 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
mmpL5 | 778298 | c.183G>A | synonymous_variant | 0.94 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
Rv3083 | 3448567 | p.His22Asp | missense_variant | 0.64 | ethionamide | Uncertain significance |
aftB | 4267272 | p.Lys522Arg | missense_variant | 0.93 | ethambutol | Not assoc w R |