TB-Profiler result

Run: ERR1215483
Summary

Run ID: ERR1215483

Sample name:

Date: 31-03-2023 12:47:11

Number of reads: 528020

Percentage reads mapped: 97.52

Strain: lineage4.3.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.1 Euro-American (LAM) LAM9 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8930 c.1629C>T synonymous_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 0.93
rpoB 759776 c.-31T>G upstream_gene_variant 0.22
rpoB 760493 c.687C>T synonymous_variant 0.17
rpoB 760519 p.Thr238Ile missense_variant 0.13
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 765219 p.Glu617Gly missense_variant 0.13
rpoC 765781 c.2412C>T synonymous_variant 0.14
rpoC 766901 p.Gly1178Ser missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800830 p.Gly8Ser missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476007 n.2350T>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156404 c.-293G>A upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289412 c.-171C>T upstream_gene_variant 0.14
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449945 p.Gly481Asp missense_variant 0.17
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4040167 p.Ala180Thr missense_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245308 c.2076G>A synonymous_variant 0.15
embB 4246643 p.Thr44Ala missense_variant 0.18
embB 4249404 p.Thr964Ile missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0