TB-Profiler result

Run: ERR1274699
Summary

Run ID: ERR1274699

Sample name:

Date: 31-03-2023 13:29:15

Number of reads: 20519

Percentage reads mapped: 98.61

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 761147 c.1341C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765719 p.Glu784Gln missense_variant 1.0
fbiC 1304085 c.1155C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471819 n.-27C>G upstream_gene_variant 0.33
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.18
rrs 1472792 n.947G>T non_coding_transcript_exon_variant 0.15
rrs 1473112 n.1267A>C non_coding_transcript_exon_variant 0.14
PPE35 2168765 p.Ser616Arg missense_variant 0.12
PPE35 2169122 c.1491C>G synonymous_variant 0.25
PPE35 2169317 c.1296C>T synonymous_variant 0.29
PPE35 2169671 c.942C>G synonymous_variant 0.25
PPE35 2169674 c.939T>C synonymous_variant 0.25
PPE35 2169680 c.933A>G synonymous_variant 0.25
PPE35 2170048 p.Leu189Val missense_variant 0.4
PPE35 2170053 p.Thr187Ser missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714747 p.Leu196Ile missense_variant 1.0
ahpC 2726670 p.Glu160* stop_gained 0.67
clpC1 4039821 p.Ala295Val missense_variant 0.5
aftB 4267325 c.1512G>T synonymous_variant 1.0