TB-Profiler result

Run: ERR1633892
Summary

Run ID: ERR1633892

Sample name:

Date: 18-08-2022 14:49:02

Number of reads: 1971587

Percentage reads mapped: 99.66

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 766406 p.Arg1013Cys missense_variant 0.2
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289560 c.-319T>A upstream_gene_variant 0.13
folC 2747747 c.-149C>A upstream_gene_variant 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiA 3641359 p.Gly273Arg missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
ubiA 4269046 p.Ala263Val missense_variant 0.17
ubiA 4269243 c.591T>C synonymous_variant 0.2
ethR 4327822 p.Glu92Lys missense_variant 0.2
ethR 4327857 p.Trp103Cys missense_variant 0.2
ethR 4327994 p.Thr149Met missense_variant 1.0