TB-Profiler result

Run: ERR1679632
Summary

Run ID: ERR1679632

Sample name:

Date: 31-03-2023 14:54:56

Number of reads: 519536

Percentage reads mapped: 99.63

Strain: lineage4.6.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 1.0
lineage4.6.2.2 Euro-American (Cameroon) LAM10-CAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7802 c.501C>G synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 767245 c.3876C>T synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801224 p.His139Leu missense_variant 0.11
fbiC 1303884 c.954T>C synonymous_variant 0.19
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169560 c.1053G>A synonymous_variant 0.11
PPE35 2169732 p.Asn294Ser missense_variant 0.12
Rv1979c 2221746 c.1416_1418dupCCG disruptive_inframe_insertion 0.97
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714764 p.Leu190Pro missense_variant 0.12
Rv2752c 3064864 p.Pro443Leu missense_variant 1.0
thyX 3067474 p.Pro158Ala missense_variant 1.0
Rv3083 3448567 p.His22Asp missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612571 c.546C>T synonymous_variant 1.0
embC 4241003 p.Ala381Pro missense_variant 0.67
embC 4242232 c.2370T>C synonymous_variant 0.2
embA 4242550 c.-683C>G upstream_gene_variant 1.0
embC 4242573 p.Glu904Gly missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248293 p.His594Tyr missense_variant 0.12
aftB 4267272 p.Lys522Arg missense_variant 1.0
ethR 4326739 c.-810G>C upstream_gene_variant 1.0
ethA 4328004 c.-531C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0