TB-Profiler result

Run: ERR1750881
Summary

Run ID: ERR1750881

Sample name:

Date: 31-03-2023 14:58:06

Number of reads: 4115159

Percentage reads mapped: 94.51

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781435 c.-125G>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471929 n.84C>G non_coding_transcript_exon_variant 0.11
rrs 1471930 n.85G>C non_coding_transcript_exon_variant 0.1
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.1
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.11
rrs 1471992 n.147A>T non_coding_transcript_exon_variant 0.18
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.11
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.15
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.12
rrs 1472221 n.376G>C non_coding_transcript_exon_variant 0.11
rrs 1472230 n.385C>G non_coding_transcript_exon_variant 0.12
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.12
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.16
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.19
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.14
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.28
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 0.14
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.22
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.12
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.13
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.13
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.18
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.27
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.3
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.25
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.17
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.15
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.15
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.15
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.21
rrl 1474548 n.891T>C non_coding_transcript_exon_variant 0.12
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.19
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.16
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.13
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.13
rrl 1475080 n.1423G>T non_coding_transcript_exon_variant 0.14
rrl 1475081 n.1424C>G non_coding_transcript_exon_variant 0.14
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.13
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.19
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.21
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.2
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.1
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.11
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.11
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.1
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.11
rrl 1475969 n.2312T>C non_coding_transcript_exon_variant 0.15
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.17
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.17
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.14
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.13
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.13
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.15
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.14
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.14
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.18
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.12
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 0.98
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407798 c.405G>T synonymous_variant 1.0