TB-Profiler result

Run: ERR1950035
Summary

Run ID: ERR1950035

Sample name:

Date: 31-03-2023 15:38:09

Number of reads: 881436

Percentage reads mapped: 99.64

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7946 c.645C>A synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1304164 p.Gly412Arg missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155215 c.897C>T synonymous_variant 0.12
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169063 p.Met517Lys missense_variant 0.17
PPE35 2169137 c.1476G>A synonymous_variant 0.12
PPE35 2169506 c.1107G>T synonymous_variant 0.21
PPE35 2170048 p.Leu189Val missense_variant 0.26
PPE35 2170053 p.Thr187Ser missense_variant 0.26
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289664 c.-423G>C upstream_gene_variant 0.11
kasA 2518692 p.Ala193Asp missense_variant 0.15
kasA 2518697 p.Cys195Gly missense_variant 0.15
eis 2714876 p.Ala153Pro missense_variant 0.13
folC 2746761 p.Gln280Lys missense_variant 0.12
fbiB 3642653 c.1119C>T synonymous_variant 0.13
rpoA 3878490 c.18C>G synonymous_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247028 p.Leu172Gln missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0