TB-Profiler result

Run: ERR1950039
Summary

Run ID: ERR1950039

Sample name:

Date: 31-03-2023 15:38:15

Number of reads: 968238

Percentage reads mapped: 99.62

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491618 p.Gln279Arg missense_variant 0.1
mshA 575190 c.-158G>A upstream_gene_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1674041 p.Gly201Glu missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101659 p.Ala462Thr missense_variant 0.12
katG 2156392 c.-282delG upstream_gene_variant 0.17
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2168876 p.Phe579Leu missense_variant 0.27
PPE35 2169713 c.900C>G synonymous_variant 0.11
PPE35 2169717 p.Asn299Ile missense_variant 0.11
PPE35 2169725 c.888T>C synonymous_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987202 p.Arg122Trp missense_variant 0.12
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3475138 p.Thr378Ala missense_variant 0.11
whiB7 3568833 c.-154C>T upstream_gene_variant 0.63
rpoA 3878490 c.18C>G synonymous_variant 0.19
embC 4241824 c.1962T>C synonymous_variant 0.1
embC 4242015 p.Phe718Ser missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267599 p.Phe413Ser missense_variant 0.1
aftB 4268619 p.Val73Gly missense_variant 0.22
aftB 4269750 c.-914A>G upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407724 p.Leu160Pro missense_variant 0.17
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0