TB-Profiler result

Run: ERR1950045
Summary

Run ID: ERR1950045

Sample name:

Date: 31-03-2023 15:38:26

Number of reads: 1036933

Percentage reads mapped: 99.67

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491623 c.843delC frameshift_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475911 n.2254T>A non_coding_transcript_exon_variant 0.11
rrl 1476187 n.2533delC non_coding_transcript_exon_variant 0.1
fabG1 1673525 p.Leu29Pro missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167824 p.Gly930Asp missense_variant 0.12
PPE35 2168728 p.Gly629Arg missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746543 c.1056C>T synonymous_variant 0.11
Rv2752c 3064588 p.Arg535Leu missense_variant 0.11
Rv2752c 3065693 p.His167Tyr missense_variant 0.12
fbiB 3642164 c.630C>T synonymous_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethR 4328102 c.555_560delGTCATT disruptive_inframe_deletion 0.12
ethR 4328111 p.Ala188Gly missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0