TB-Profiler result

Run: ERR1950068
Summary

Run ID: ERR1950068

Sample name:

Date: 31-03-2023 15:39:02

Number of reads: 986036

Percentage reads mapped: 99.8

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 620158 p.Leu90Ile missense_variant 0.25
rpoB 762556 p.Pro917Leu missense_variant 0.14
rpoC 764361 c.993delC frameshift_variant 0.12
rpoC 767049 p.Gln1227Arg missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
atpE 1460935 c.-110T>A upstream_gene_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rpsA 1834543 c.1002C>G synonymous_variant 0.12
rpsA 1834949 c.1409delT frameshift_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155216 p.Gly299Val missense_variant 0.11
PPE35 2168728 p.Gly629Arg missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3064606 p.Ile529Thr missense_variant 0.14
fbiA 3641206 p.Ala222Ser missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246536 p.Arg8His missense_variant 0.12
embB 4247028 p.Leu172Gln missense_variant 0.19
embB 4247059 c.546C>G synonymous_variant 0.11
embB 4247060 p.Pro183Ala missense_variant 0.1
embB 4247066 p.Ile185Val missense_variant 0.1
aftB 4268623 p.Trp72Gly missense_variant 0.21
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0