TB-Profiler result

Run: ERR1950089
Summary

Run ID: ERR1950089

Sample name:

Date: 31-03-2023 15:39:36

Number of reads: 1211338

Percentage reads mapped: 99.38

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491315 p.Gly178Ala missense_variant 0.2
rpoC 766643 p.Glu1092Lys missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777808 p.Ser225Ala missense_variant 0.2
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1305033 c.2103T>G synonymous_variant 0.31
Rv1258c 1407039 p.Val101Gly missense_variant 0.38
embR 1416587 p.Ile254Ser missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168306 c.2307C>T synonymous_variant 0.18
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169468 p.Phe382Ser missense_variant 0.1
PPE35 2170447 p.Ser56Ala missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290164 c.-923A>T upstream_gene_variant 0.2
fprA 3474162 c.156G>T synonymous_variant 0.17
fprA 3474634 p.Leu210Val missense_variant 0.22
Rv3236c 3612581 p.Leu179Arg missense_variant 0.2
fbiA 3640450 c.-93T>C upstream_gene_variant 0.14
fbiB 3642280 p.Leu249Arg missense_variant 0.31
rpoA 3878490 c.18C>G synonymous_variant 0.43
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244890 p.Ile553Ser missense_variant 0.21
aftB 4267560 p.Ala426Asp missense_variant 0.16
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0