TB-Profiler result

Run: ERR2036917
Summary

Run ID: ERR2036917

Sample name:

Date: 31-03-2023 15:43:31

Number of reads: 300035

Percentage reads mapped: 98.85

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775715 c.2766G>A synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305494 p.Ala855Val missense_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473504 n.-154A>C upstream_gene_variant 1.0
rrl 1475662 n.2005C>T non_coding_transcript_exon_variant 1.0
inhA 1674280 c.82dupG frameshift_variant 0.15
inhA 1674956 p.Ala252Val missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169523 p.Ala364Thr missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747098 c.501C>A synonymous_variant 0.2
folC 2747405 p.Pro65Leu missense_variant 0.33
Rv2752c 3065611 p.Thr194Ser missense_variant 1.0
fbiB 3641701 p.Cys56Phe missense_variant 0.5
rpoA 3878493 p.Gln5His missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244210 c.978G>A synonymous_variant 0.4
embB 4249720 c.3207C>A synonymous_variant 0.25
embB 4249732 c.3219C>G synonymous_variant 1.0
ethA 4326073 c.1401C>A synonymous_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407590 p.Ala205Thr missense_variant 1.0