TB-Profiler result

Run: ERR2179668
Summary

Run ID: ERR2179668

Sample name:

Date: 19-10-2023 22:07:50

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.5 Euro-American H;T RD122 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 0.96
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 0.97
mmpR5 778121 c.-869G>A upstream_gene_variant 0.97
mmpL5 778301 p.Gln60His missense_variant 0.9
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833734 p.Ala65Thr missense_variant 0.89
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 0.94
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714211 c.1122G>A synonymous_variant 0.97
thyX 3068084 c.-139T>G upstream_gene_variant 0.87
ald 3087695 p.Asp292Glu missense_variant 0.3
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3840415 p.Pro336Ser missense_variant 0.91
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
ddn 3986759 c.-85C>T upstream_gene_variant 0.97
clpC1 4038318 p.Pro796Leu missense_variant 0.97
clpC1 4040745 c.-41G>A upstream_gene_variant 0.98
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0