TB-Profiler result

Run: ERR2179808
Summary

Run ID: ERR2179808

Sample name:

Date: 19-10-2023 23:11:14

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5684 p.Val149Ile missense_variant 0.98
gyrB 6247 p.Lys336Asn missense_variant 0.99
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 8715 p.Pro472Ser missense_variant 0.99
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 0.99
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778244 c.-746G>C upstream_gene_variant 0.99
mmpS5 778614 p.Ser98Ala missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406987 c.354G>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.99
Rv3083 3448478 c.-25delG upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 0.99
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407641 p.Val188Leu missense_variant 1.0
PPE35 2164492 c.1083_*3156del frameshift_variant&stop_lost&splice_region_variant 0.91
folC 2744108 c.-28182_*2026del transcript_ablation 0.93
folC 2747194 c.-14689_404del frameshift_variant&start_lost 0.92
fbiD 3337327 c.-1790_*23137del transcript_ablation 0.9
Rv3236c 3608504 c.-23350_*3454del transcript_ablation 0.91
alr 3811305 c.-13525_*28888del transcript_ablation 0.93
alr 3835785 c.-15543_*4408del transcript_ablation 0.9
embC 4199607 c.-40255_*6248del transcript_ablation 0.95
embC 4201096 c.-38766_*5601del transcript_ablation 0.92
embC 4217305 c.-22557_*44del transcript_ablation 0.92
embB 4245524 c.-989_2246del frameshift_variant&start_lost 0.91
ubiA 4267931 c.-6691_*993del transcript_ablation 0.93