TB-Profiler result

Run: ERR2228809
Summary

Run ID: ERR2228809

Sample name:

Date: 31-03-2023 16:21:44

Number of reads: 1376149

Percentage reads mapped: 99.37

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6416 p.Thr393Pro missense_variant 0.22
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.23
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673732 p.Met98Lys missense_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918490 p.Gln184Leu missense_variant 0.26
katG 2154031 p.Val694Gly missense_variant 0.18
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169623 c.990T>C synonymous_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746642 c.957T>G synonymous_variant 0.12
Rv2752c 3064566 c.1626G>C synonymous_variant 0.23
fbiD 3339676 p.Cys187Gly missense_variant 0.15
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3236c 3613076 p.Leu14Gln missense_variant 0.17
rpoA 3877735 p.Val258Gly missense_variant 0.23
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246549 c.36A>G synonymous_variant 0.13
embB 4247040 p.Phe176Cys missense_variant 0.35
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0