TB-Profiler result

Run: ERR2228820
Summary

Run ID: ERR2228820

Sample name:

Date: 31-03-2023 16:22:05

Number of reads: 1427459

Percentage reads mapped: 99.39

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 765709 p.Glu780Asp missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777852 p.Val210Ala missense_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1305033 c.2103T>G synonymous_variant 0.29
Rv1258c 1406558 c.783T>G synonymous_variant 0.14
atpE 1461073 p.Leu10Arg missense_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1476441 n.2784T>G non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918607 p.Val223Gly missense_variant 0.24
katG 2154858 c.1254A>G synonymous_variant 0.17
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169049 p.Ile522Phe missense_variant 0.29
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289936 c.-695T>C upstream_gene_variant 0.14
folC 2747744 c.-146A>T upstream_gene_variant 0.27
pepQ 2860129 p.Phe97Cys missense_variant 0.22
ribD 2986670 c.-169A>G upstream_gene_variant 0.12
Rv2752c 3065747 p.Ser149Thr missense_variant 0.16
Rv3236c 3612508 c.609T>G synonymous_variant 0.21
fbiB 3642216 p.Thr228Pro missense_variant 0.28
rpoA 3878490 c.18C>G synonymous_variant 0.3
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249664 p.Thr1051Ala missense_variant 0.2
ubiA 4269869 c.-36delG upstream_gene_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448500 c.-3_*1408del transcript_ablation 1.0