TB-Profiler result

Run: ERR2228837
Summary

Run ID: ERR2228837

Sample name:

Date: 31-03-2023 16:22:37

Number of reads: 1824328

Percentage reads mapped: 99.24

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 0.99
ccsA 619831 c.-60T>G upstream_gene_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 0.98
mmpL5 776539 p.Met648Val missense_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
Rv1258c 1407039 p.Val101Gly missense_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1674076 p.Thr213Ala missense_variant 0.14
rpsA 1834695 p.Asp385Gly missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918607 p.Val223Gly missense_variant 0.22
PPE35 2168728 p.Gly629Arg missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518605 p.Val164Gly missense_variant 0.17
pepQ 2860144 p.Val92Gly missense_variant 0.23
Rv2752c 3064567 p.Gly542Val missense_variant 0.18
rpoA 3878663 c.-156A>G upstream_gene_variant 0.2
clpC1 4040106 p.Val200Gly missense_variant 0.26
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249592 p.Thr1027Ala missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0