TB-Profiler result

Run: ERR2228902
Summary

Run ID: ERR2228902

Sample name:

Date: 31-03-2023 16:25:22

Number of reads: 144521

Percentage reads mapped: 99.61

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5409 p.Ala57Val missense_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8891 p.Lys530Asn missense_variant 0.22
rpoC 765124 c.1755G>T synonymous_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777164 c.1317C>T synonymous_variant 0.4
mmpL5 777354 p.Val376Gly missense_variant 0.33
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800855 p.Val16Glu missense_variant 0.33
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1303826 p.Glu299Gly missense_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473634 n.-24A>T upstream_gene_variant 0.4
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474035 n.378C>T non_coding_transcript_exon_variant 0.22
inhA 1674959 p.Thr253Asn missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154418 p.Val565Ala missense_variant 0.33
katG 2154437 p.Ala559Thr missense_variant 0.25
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.67
PPE35 2170053 p.Thr187Ser missense_variant 0.5
Rv1979c 2222246 p.Gly307* stop_gained 0.5
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987320 p.Glu161Gly missense_variant 1.0
ald 3086827 p.Val3Gly missense_variant 0.67
alr 3841554 c.-134T>A upstream_gene_variant 0.67
ddn 3987151 p.Lys103Ile missense_variant 0.4
clpC1 4039684 p.Arg341Ser missense_variant 0.5
clpC1 4039691 c.1014G>C synonymous_variant 0.4
embC 4242540 p.Ser893Phe missense_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243340 c.108G>A synonymous_variant 0.18
embB 4247571 p.Pro353Arg missense_variant 1.0
ethA 4327788 c.-315G>A upstream_gene_variant 0.4
whiB6 4338261 c.261G>C synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407579 c.623delG frameshift_variant 0.18
gid 4408195 p.Pro3Leu missense_variant 0.22