TB-Profiler result

Run: ERR2228906

Summary

Run ID: ERR2228906

Sample name:

Date: 31-03-2023 16:25:36

Number of reads: 994823

Percentage reads mapped: 99.59

Strain: lineage4.8

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491453 p.Gly224Asp missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776087 c.2394C>G synonymous_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
Rv1258c 1407243 p.Leu33Pro missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1476086 n.2429G>T non_coding_transcript_exon_variant 0.12
rrl 1476212 n.2555T>A non_coding_transcript_exon_variant 0.13
fabG1 1673560 p.Lys41Leu missense_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102389 c.654G>C synonymous_variant 0.11
PPE35 2168152 p.Thr821Ala missense_variant 0.11
PPE35 2168728 p.Gly629Arg missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289871 c.-630T>C upstream_gene_variant 0.11
Rv2752c 3064566 c.1626G>C synonymous_variant 0.27
Rv3083 3448381 c.-123T>A upstream_gene_variant 0.11
Rv3236c 3612103 c.1013delT frameshift_variant 0.25
clpC1 4038575 c.2130C>A synonymous_variant 0.11
clpC1 4039003 p.Asn568Asp missense_variant 0.11
clpC1 4039220 c.1485G>A synonymous_variant 0.12
clpC1 4039428 p.Glu426Val missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247028 p.Leu172Pro missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0