TB-Profiler result

Run: ERR2228938
Summary

Run ID: ERR2228938

Sample name:

Date: 31-03-2023 16:26:52

Number of reads: 483465

Percentage reads mapped: 99.69

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576751 p.Lys468Asn missense_variant 0.38
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776254 p.Lys743Glu missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.17
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102139 p.Arg302Trp missense_variant 0.11
katG 2155257 c.855C>T synonymous_variant 0.12
PPE35 2168728 p.Gly629Arg missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.17
Rv2752c 3067086 c.-895A>T upstream_gene_variant 0.1
ald 3086861 p.Phe14Leu missense_variant 0.14
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
ddn 3987203 c.360C>T synonymous_variant 0.1
embC 4241633 p.Gly591Arg missense_variant 0.14
embC 4242232 c.2370T>C synonymous_variant 0.19
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244591 c.1359G>C synonymous_variant 0.1
aftB 4268531 c.306C>A synonymous_variant 0.11
ubiA 4269511 p.Val108Gly missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0