TB-Profiler result

Run: ERR2228950
Summary

Run ID: ERR2228950

Sample name:

Date: 31-03-2023 16:27:43

Number of reads: 1241368

Percentage reads mapped: 99.57

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169063 p.Met517Lys missense_variant 0.19
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448482 c.-22G>T upstream_gene_variant 0.33
Rv3236c 3613071 p.Ala16Thr missense_variant 0.13
rpoA 3878490 c.18C>G synonymous_variant 0.32
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268623 p.Trp72Gly missense_variant 0.21
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448508 c.6_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0