TB-Profiler result

Run: ERR2229072
Summary

Run ID: ERR2229072

Sample name:

Date: 18-08-2022 10:33:38

Number of reads: 201276

Percentage reads mapped: 99.06

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.95
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5681 p.Gln148* stop_gained 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476220 n.2563G>T non_coding_transcript_exon_variant 0.2
fabG1 1673380 c.-60C>G upstream_gene_variant 0.2
alr 3841546 c.-126C>A upstream_gene_variant 0.29
alr 3841582 c.-162A>G upstream_gene_variant 0.17
alr 3841584 c.-164C>A upstream_gene_variant 0.18
alr 3841589 c.-170delG upstream_gene_variant 0.2
alr 3841612 c.-193_-192insC upstream_gene_variant 0.25
embB 4248227 p.Trp572Arg missense_variant 0.14
ethR 4328134 p.Glu196* stop_gained 0.17
ethR 4328143 p.Val199Leu missense_variant 0.17