TB-Profiler result

Run: ERR2229245
Summary

Run ID: ERR2229245

Sample name:

Date: 31-03-2023 16:52:14

Number of reads: 1360030

Percentage reads mapped: 99.11

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 779115 p.Trp42Cys missense_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800737 c.-72T>C upstream_gene_variant 0.12
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918547 p.Leu203Ser missense_variant 0.2
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169902 c.711G>C synonymous_variant 0.15
PPE35 2170048 p.Leu189Val missense_variant 0.38
PPE35 2170053 p.Thr187Ser missense_variant 0.41
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289704 c.-463G>T upstream_gene_variant 0.13
kasA 2518864 c.750G>C synonymous_variant 0.15
folC 2746615 c.984C>A synonymous_variant 0.12
pepQ 2860152 p.Glu89Asp missense_variant 0.14
pepQ 2860182 c.237C>G synonymous_variant 0.12
Rv3083 3448365 c.-139T>C upstream_gene_variant 0.13
fbiA 3640489 c.-54C>A upstream_gene_variant 0.15
fbiB 3642162 p.Thr210Pro missense_variant 0.2
alr 3841546 c.-126C>A upstream_gene_variant 0.2
panD 4044398 c.-117T>A upstream_gene_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246567 c.54_55insT frameshift_variant 0.2
embB 4246584 p.Arg24Pro missense_variant 0.2
aftB 4267929 p.Arg303Leu missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0