TB-Profiler result

Run: ERR2229303
Summary

Run ID: ERR2229303

Sample name:

Date: 18-08-2022 11:15:00

Number of reads: 1276233

Percentage reads mapped: 98.91

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.19
rpoC 765803 p.Thr812Pro missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.19
inhA 1674496 p.Pro99Thr missense_variant 0.12
rpsA 1834800 p.Glu420Gly missense_variant 0.11
tlyA 1917774 c.-166C>A upstream_gene_variant 0.13
kasA 2518879 c.765A>G synonymous_variant 0.15
kasA 2518882 c.768C>A synonymous_variant 0.16
kasA 2519163 p.Val350Ala missense_variant 0.12
thyA 3074488 c.-17C>T upstream_gene_variant 0.11
fbiB 3642442 p.Pro303Gln missense_variant 0.12
alr 3841546 c.-126C>A upstream_gene_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244252 p.Ser340Arg missense_variant 0.13
embB 4246765 c.252G>A synonymous_variant 0.13