TB-Profiler result

Run: ERR2229405
Summary

Run ID: ERR2229405

Sample name:

Date: 31-03-2023 17:09:46

Number of reads: 179735

Percentage reads mapped: 99.26

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7208 p.Asp657Asn missense_variant 0.2
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8304 p.Thr335Ala missense_variant 0.33
gyrA 8601 p.Ala434Ser missense_variant 0.29
mshA 575167 c.-181G>T upstream_gene_variant 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781427 c.-133G>A upstream_gene_variant 0.25
fbiC 1302786 c.-145C>A upstream_gene_variant 0.33
embR 1416297 p.His351Tyr missense_variant 0.25
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473713 n.56A>G non_coding_transcript_exon_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
inhA 1674843 p.Gln214His missense_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169278 c.1335T>C synonymous_variant 0.33
PPE35 2169281 c.1332T>G synonymous_variant 0.33
PPE35 2169287 c.1326T>C synonymous_variant 0.25
PPE35 2169902 p.Leu237Phe missense_variant 0.17
PPE35 2169910 p.Asn235Tyr missense_variant 0.15
PPE35 2170392 p.Gly74Ala missense_variant 0.18
PPE35 2170400 c.213G>C synonymous_variant 0.18
Rv1979c 2222544 p.Leu207Phe missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288879 c.363G>A synonymous_variant 0.29
folC 2747046 p.Asn185Asp missense_variant 0.25
folC 2747332 c.267G>A synonymous_variant 0.29
Rv3236c 3612958 c.159C>A synonymous_variant 0.29
fbiA 3640552 p.Thr4Ser missense_variant 0.33
alr 3841546 c.-126C>A upstream_gene_variant 0.36
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246555 c.42G>C synonymous_variant 0.75
embB 4246556 p.Ala15Pro missense_variant 0.75
embB 4246563 p.Leu17Trp missense_variant 0.67
embB 4246567 c.54G>T synonymous_variant 0.67
aftB 4268819 p.Leu6Phe missense_variant 0.67
ethR 4327949 p.Val134Gly missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408431 c.-229G>A upstream_gene_variant 0.29
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0