TB-Profiler result

Run: ERR2229493
Summary

Run ID: ERR2229493

Sample name:

Date: 18-08-2022 10:32:18

Number of reads: 356391

Percentage reads mapped: 99.31

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6158 p.Thr307Pro missense_variant 0.18
gyrB 6225 p.Asn329Ser missense_variant 0.15
gyrA 7346 c.45C>A synonymous_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8269 c.970delG frameshift_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475218 n.1561C>A non_coding_transcript_exon_variant 0.18
rrl 1475802 n.2145G>A non_coding_transcript_exon_variant 0.2
fabG1 1673357 c.-83G>A upstream_gene_variant 0.25
fabG1 1673359 c.-81T>C upstream_gene_variant 0.27
fabG1 1673361 c.-79C>G upstream_gene_variant 0.3
fabG1 1673380 c.-60C>G upstream_gene_variant 0.5
rpsA 1833592 c.51C>G synonymous_variant 0.14
ribD 2986838 c.-1C>T upstream_gene_variant 0.15
fbiA 3640681 p.Val47Phe missense_variant 0.2
alr 3841546 c.-126C>A upstream_gene_variant 0.18
alr 3841552 c.-132C>T upstream_gene_variant 0.14
alr 3841612 c.-193_-192insC upstream_gene_variant 0.18
panD 4044017 p.Ala89Ser missense_variant 0.2
embB 4247427 p.Gly305Ala missense_variant 0.2
ethA 4326297 p.Leu393Met missense_variant 0.14
ethR 4327335 c.-214A>G upstream_gene_variant 0.18