TB-Profiler result

Run: ERR2229590

Summary

Run ID: ERR2229590

Sample name:

Date: 18-08-2022 10:58:08

Number of reads: 301658

Percentage reads mapped: 98.97

Strain: lineage4.8

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
fgd1 490742 c.-41C>T upstream_gene_variant 0.17
fgd1 490744 c.-39T>C upstream_gene_variant 0.17
rpoB 762307 p.Pro834Leu missense_variant 0.15
fbiC 1302845 c.-86T>G upstream_gene_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473744 n.87T>C non_coding_transcript_exon_variant 0.17
fabG1 1673380 c.-60C>G upstream_gene_variant 0.15
rpsA 1833459 c.-83T>C upstream_gene_variant 0.17
katG 2156130 c.-19A>G upstream_gene_variant 0.18
katG 2156138 c.-27A>T upstream_gene_variant 0.17
embC 4241038 c.1176G>A synonymous_variant 0.17