TB-Profiler result

Run: ERR2229611
Summary

Run ID: ERR2229611

Sample name:

Date: 18-08-2022 10:57:26

Number of reads: 467294

Percentage reads mapped: 99.02

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7583 p.Asp94Glu missense_variant 0.12
gyrA 8995 p.Asp565Val missense_variant 0.13
rpoB 761895 p.Ala697Ser missense_variant 0.17
rpoC 763115 c.-255T>A upstream_gene_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.14
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673322 c.-118C>A upstream_gene_variant 0.2
fabG1 1673346 c.-94C>G upstream_gene_variant 0.24
fabG1 1673349 c.-91G>C upstream_gene_variant 0.36
fabG1 1673357 c.-83G>A upstream_gene_variant 0.13
fabG1 1673359 c.-81T>C upstream_gene_variant 0.13
fabG1 1673361 c.-79C>G upstream_gene_variant 0.13
fabG1 1673378 c.-62C>A upstream_gene_variant 0.14
fabG1 1673380 c.-60C>G upstream_gene_variant 0.64
eis 2715330 c.3G>T synonymous_variant 0.2
ald 3087842 c.1023A>G synonymous_variant 0.17
fbiB 3642709 p.Gly392Val missense_variant 0.18
alr 3841546 c.-126C>A upstream_gene_variant 0.28
embB 4248203 p.Pro564Ala missense_variant 0.15
embB 4248390 p.Met626Thr missense_variant 0.13
ethA 4326151 c.1323C>A synonymous_variant 0.12
ethR 4326961 c.-588G>C upstream_gene_variant 0.2
ethR 4326964 c.-585G>A upstream_gene_variant 0.2
ethR 4326970 c.-579G>T upstream_gene_variant 0.33
ethR 4328111 p.Ala188Val missense_variant 0.17