TB-Profiler result

Run: ERR2229684
Summary

Run ID: ERR2229684

Sample name:

Date: 31-03-2023 17:24:54

Number of reads: 97494

Percentage reads mapped: 97.75

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490811 p.Ala10Val missense_variant 1.0
rpoC 763378 c.9C>T synonymous_variant 0.5
rpoC 766562 p.Thr1065Ser missense_variant 0.67
mmpL5 778474 p.Val3Met missense_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.5
rpsA 1834367 p.Leu276Phe missense_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 1.0
PPE35 2170053 p.Thr187Ser missense_variant 1.0
folC 2746201 c.1398C>T synonymous_variant 1.0
fbiD 3339217 p.Thr34Pro missense_variant 0.67
Rv3236c 3613252 c.-136G>A upstream_gene_variant 1.0
alr 3841546 c.-126C>A upstream_gene_variant 0.29
alr 3841612 c.-193_-192insC upstream_gene_variant 0.33
clpC1 4039492 p.Glu405Lys missense_variant 0.67
embB 4246544 p.Thr11Pro missense_variant 0.67
ethR 4328102 p.Ala185Val missense_variant 1.0