TB-Profiler result

Run: ERR2229714
Summary

Run ID: ERR2229714

Sample name:

Date: 31-03-2023 17:28:23

Number of reads: 181516

Percentage reads mapped: 99.05

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7946 c.645C>A synonymous_variant 0.4
gyrA 9409 p.Met703Lys missense_variant 0.25
gyrA 9554 c.2253G>A synonymous_variant 0.67
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
embR 1416433 c.915C>T synonymous_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168053 p.Val854Leu missense_variant 0.33
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2168876 c.1737C>T synonymous_variant 0.5
PPE35 2169902 c.711G>C synonymous_variant 0.12
PPE35 2170048 p.Leu189Val missense_variant 0.53
PPE35 2170053 p.Thr187Ser missense_variant 0.58
PPE35 2170159 p.Ala152Ser missense_variant 0.13
PPE35 2170178 c.435T>C synonymous_variant 0.12
PPE35 2170189 p.Glu142Gln missense_variant 0.13
PPE35 2170280 c.333C>G synonymous_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223358 c.-194C>A upstream_gene_variant 0.33
folC 2746863 p.Leu246Met missense_variant 0.2
pepQ 2860159 p.Ala87Asp missense_variant 0.4
whiB7 3568640 p.Arg14Gly missense_variant 0.29
alr 3841546 c.-126C>A upstream_gene_variant 0.2
clpC1 4039674 p.Pro344Gln missense_variant 0.38
clpC1 4040822 c.-118C>T upstream_gene_variant 0.4
panD 4044312 c.-31G>C upstream_gene_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248464 p.Ser651Gly missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407621 c.582C>T synonymous_variant 0.67
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0