TB-Profiler result

Run: ERR2229716
Summary

Run ID: ERR2229716

Sample name:

Date: 31-03-2023 17:28:32

Number of reads: 917860

Percentage reads mapped: 99.11

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 763801 c.432C>A synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1304857 p.Thr643Ala missense_variant 0.1
embR 1416998 p.Ala117Asp missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474131 n.474C>A non_coding_transcript_exon_variant 0.11
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167709 c.2904C>T synonymous_variant 0.14
PPE35 2168728 p.Gly629Arg missense_variant 0.95
PPE35 2169317 p.Phe432Leu missense_variant 0.15
PPE35 2169366 p.Ser416Ile missense_variant 0.12
PPE35 2169571 p.Ser348Gly missense_variant 0.1
PPE35 2169797 c.816G>T synonymous_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyX 3067512 p.Glu145Ala missense_variant 0.1
Rv3083 3448460 c.-44C>A upstream_gene_variant 0.15
fprA 3475213 p.Ala403Thr missense_variant 0.18
fbiB 3642197 c.663C>A synonymous_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244533 p.Thr434Ile missense_variant 0.12
embA 4244591 c.1359G>A synonymous_variant 0.17
ubiA 4270022 c.-189C>G upstream_gene_variant 0.11
ubiA 4270025 c.-192C>G upstream_gene_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0