TB-Profiler result

Run: ERR2229799
Summary

Run ID: ERR2229799

Sample name:

Date: 31-03-2023 17:35:58

Number of reads: 914067

Percentage reads mapped: 99.67

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7445 c.144C>T synonymous_variant 0.12
gyrA 7446 p.Lys49Glu missense_variant 0.12
rpoB 762607 p.Ala934Asp missense_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673873 p.Trp145Leu missense_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2170315 p.Val100Leu missense_variant 0.1
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289941 c.-700C>T upstream_gene_variant 0.11
ahpC 2726350 p.Trp53Leu missense_variant 0.19
folC 2746748 p.Gly284Val missense_variant 0.12
folC 2747759 c.-161T>C upstream_gene_variant 0.11
thyA 3074648 c.-177T>G upstream_gene_variant 0.33
fprA 3474919 p.Lys305Gln missense_variant 0.14
fprA 3474922 p.Asp306His missense_variant 0.15
fbiB 3641972 c.438G>T synonymous_variant 0.12
embC 4240521 p.Thr220Asn missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246647 p.Pro45Leu missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0