TB-Profiler result

Run: ERR2245358
Summary

Run ID: ERR2245358

Sample name:

Date: 31-03-2023 17:39:27

Number of reads: 1889159

Percentage reads mapped: 98.41

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8414 c.1113C>T synonymous_variant 1.0
gyrA 9431 c.2130G>T synonymous_variant 0.5
ccsA 619830 c.-61G>T upstream_gene_variant 0.5
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302826 c.-105G>A upstream_gene_variant 0.67
rrl 1473541 n.-117G>A upstream_gene_variant 0.67
ndh 2102685 p.Gly120Cys missense_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223361 c.-197C>A upstream_gene_variant 1.0
pepQ 2859484 p.Ser312Tyr missense_variant 0.5
fbiD 3339685 p.Asp190Tyr missense_variant 1.0
fprA 3474850 p.Arg282Ser missense_variant 1.0
alr 3841509 c.-89A>T upstream_gene_variant 0.67
rpoA 3878490 c.18C>G synonymous_variant 0.67
clpC1 4038553 p.Val718Ile missense_variant 0.67
clpC1 4038961 p.Met582Leu missense_variant 1.0
clpC1 4040730 c.-26T>A upstream_gene_variant 0.5
embC 4239879 p.Ala6Gly missense_variant 1.0
ethA 4327716 c.-243G>T upstream_gene_variant 0.29