TB-Profiler result

Run: ERR228188

Summary

Run ID: ERR228188

Sample name:

Date: 31-03-2023 17:47:58

Number of reads: 1943316

Percentage reads mapped: 99.73

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.98
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9056 c.1755C>T synonymous_variant 0.96
fgd1 490751 c.-32T>G upstream_gene_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ribD 2987307 p.Ala157Pro missense_variant 0.22
thyA 3073806 c.666C>G synonymous_variant 0.22
rpoA 3878569 c.-62C>G upstream_gene_variant 0.21
clpC1 4038857 c.1848C>A synonymous_variant 0.23
embC 4242425 p.Arg855Gly missense_variant 0.3
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407931 p.Leu91Pro missense_variant 0.23