TB-Profiler result

Run: ERR234212
Summary

Run ID: ERR234212

Sample name:

Date: 31-03-2023 18:03:39

Number of reads: 4943762

Percentage reads mapped: 99.94

Strain: lineage4.9

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 619831 c.-60T>G upstream_gene_variant 0.44
rpoC 762836 c.-534C>G upstream_gene_variant 0.19
rpoC 766628 p.Arg1087Gly missense_variant 0.26
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.15
PPE35 2169320 p.Leu431Phe missense_variant 0.18
PPE35 2169866 c.747G>C synonymous_variant 0.23
pepQ 2859381 c.1038C>G synonymous_variant 0.4
Rv2752c 3064552 p.Arg547Pro missense_variant 0.31
clpC1 4038857 c.1848C>A synonymous_variant 0.23
clpC1 4039932 p.Gly258Val missense_variant 0.36
embC 4239870 p.Thr3Asn missense_variant 0.2
embC 4242425 p.Arg855Gly missense_variant 0.33
embC 4242822 p.Val987Gly missense_variant 0.57
embC 4242827 p.Leu989Val missense_variant 0.19
embB 4248725 p.Ser738Ala missense_variant 0.5
ubiA 4269529 p.Ala102Gly missense_variant 0.21