TB-Profiler result

Run: ERR234227

Summary

Run ID: ERR234227

Sample name:

Date: 13-08-2022 02:52:20

Number of reads: 8590152

Percentage reads mapped: 98.95

Strain: lineage4.1.1.3

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303174 p.Leu82Val missense_variant 0.27
fbiC 1305193 p.Gly755Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833727 c.186G>A synonymous_variant 0.99
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2222257 p.Ile303Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714366 p.Val323Leu missense_variant 0.21
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.3
Rv3083 3449072 p.Val190Gly missense_variant 0.19
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642772 p.Asp413Ala missense_variant 0.23
rpoA 3878641 c.-135delG upstream_gene_variant 0.12
clpC1 4039932 p.Gly258Val missense_variant 0.27
embC 4239842 c.-21C>A upstream_gene_variant 0.16
embC 4242425 p.Arg855Gly missense_variant 0.31
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.24
embB 4249408 c.2895G>A synonymous_variant 0.99
ubiA 4269529 p.Ala102Gly missense_variant 0.24
whiB6 4338595 c.-75delG upstream_gene_variant 1.0