TB-Profiler result

Run: ERR2446421
Summary

Run ID: ERR2446421

Sample name:

Date: 15-08-2022 11:03:45

Number of reads: 373534

Percentage reads mapped: 99.98

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6049 c.810G>T synonymous_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9019 c.1721dupG frameshift_variant 0.18
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1461238 p.Phe65Tyr missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2222023 p.Ala381Asp missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288951 c.291T>C synonymous_variant 0.13
clpC1 4040302 p.Arg135Cys missense_variant 0.14
embC 4240502 p.Phe214Leu missense_variant 0.2
embC 4240783 c.921G>A synonymous_variant 0.13
ubiA 4269041 p.Asp265Tyr missense_variant 0.17
whiB6 4338595 c.-75delG upstream_gene_variant 1.0