TB-Profiler result

Run: ERR2510747
Summary

Run ID: ERR2510747

Sample name:

Date: 31-03-2023 18:55:05

Number of reads: 594852

Percentage reads mapped: 99.07

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7011 c.1774delG frameshift_variant 0.11
gyrA 7078 c.-224A>T upstream_gene_variant 0.11
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7757 c.456C>T synonymous_variant 0.12
gyrA 8991 p.His564Tyr missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460981 c.-64A>T upstream_gene_variant 0.29
atpE 1461222 p.Val60Phe missense_variant 0.25
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223028 p.Phe46Tyr missense_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518647 p.Ile178Asn missense_variant 0.14
eis 2715491 c.-159G>T upstream_gene_variant 1.0
thyX 3068024 c.-80delG upstream_gene_variant 0.11
fprA 3474115 p.Asp37Asn missense_variant 0.12
fbiB 3640974 c.-561T>C upstream_gene_variant 0.12
alr 3841546 c.-126C>A upstream_gene_variant 1.0
alr 3841612 c.-193_-192insC upstream_gene_variant 1.0
clpC1 4038596 c.2109A>G synonymous_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4326582 p.Asn298His missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0