TB-Profiler result

Run: ERR2510792
Summary

Run ID: ERR2510792

Sample name:

Date: 31-03-2023 18:56:28

Number of reads: 1177198

Percentage reads mapped: 97.26

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576482 p.Val379Leu missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.13
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.14
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.1
rrs 1472675 n.830T>A non_coding_transcript_exon_variant 0.11
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.11
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.1
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.1
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.15
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.21
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.21
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.22
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.22
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.22
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.22
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.22
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.22
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.23
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.22
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.23
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.23
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.24
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.15
rrl 1474232 n.575C>T non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.22
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.29
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.32
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.24
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.24
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.14
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
alr 3841080 p.His114Pro missense_variant 1.0
embC 4242848 p.Pro996Ala missense_variant 1.0
embB 4246536 p.Arg8Pro missense_variant 0.25
embB 4246584 p.Arg24Pro missense_variant 0.6
aftB 4268619 p.Val73Gly missense_variant 0.19
whiB6 4338595 c.-75delG upstream_gene_variant 1.0