TB-Profiler result

Run: ERR2512850

Summary

Run ID: ERR2512850

Sample name:

Date: 31-03-2023 19:17:48

Number of reads: 1268857

Percentage reads mapped: 99.13

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5929 c.690G>T synonymous_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490702 c.-81C>G upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475934 n.2277G>T non_coding_transcript_exon_variant 0.12
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.18
rrl 1475974 n.2317A>G non_coding_transcript_exon_variant 0.15
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.2
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.15
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.15
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.17
rrl 1475992 n.2335T>C non_coding_transcript_exon_variant 0.17
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.17
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.17
rrl 1476003 n.2346T>C non_coding_transcript_exon_variant 0.17
rrl 1476007 n.2350T>C non_coding_transcript_exon_variant 0.17
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.15
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.15
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.15
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.13
rrl 1476548 n.2891T>C non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170066 p.Ala183Thr missense_variant 0.12
fprA 3474271 p.Gln89Glu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0