TB-Profiler result

Run: ERR2513045
Summary

Run ID: ERR2513045

Sample name:

Date: 31-03-2023 19:25:39

Number of reads: 824260

Percentage reads mapped: 99.75

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576488 p.Val381His missense_variant 0.18
ccsA 620748 c.858T>G synonymous_variant 0.28
rpoB 759615 c.-192A>C upstream_gene_variant 0.2
rpoB 759620 c.-187A>C upstream_gene_variant 0.23
rpoC 765046 p.Met559Ile missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777164 c.1317C>T synonymous_variant 0.11
mmpL5 777173 c.1308C>T synonymous_variant 0.11
mmpL5 777176 p.Glu435Asp missense_variant 0.11
mmpR5 779346 p.Asp119Glu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304816 p.His629Arg missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474232 n.575C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154335 p.Gly593Cys missense_variant 1.0
PPE35 2170180 p.Ala145Ser missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746367 c.1231delG frameshift_variant 0.14
folC 2746534 p.Asn355Lys missense_variant 0.12
alr 3841080 p.His114Pro missense_variant 1.0
embC 4242615 p.Ala918Val missense_variant 0.18
ethA 4327510 c.-37G>A upstream_gene_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0