TB-Profiler result

Run: ERR2513632
Summary

Run ID: ERR2513632

Sample name:

Date: 31-03-2023 19:48:24

Number of reads: 695491

Percentage reads mapped: 99.72

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6358 c.-944C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 761483 c.1677G>T synonymous_variant 0.11
rpoC 763818 p.Thr150Met missense_variant 0.12
mmpL5 775614 p.Ala956Glu missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777482 c.999G>A synonymous_variant 0.1
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475128 n.1471T>C non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.67
rrl 1476570 n.2913A>G non_coding_transcript_exon_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289598 c.-358delA upstream_gene_variant 0.11
Rv2752c 3067065 c.-874G>C upstream_gene_variant 0.1
clpC1 4039691 c.1014G>C synonymous_variant 0.1
embC 4240821 p.Pro320His missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243862 c.630C>A synonymous_variant 0.12
embB 4246664 p.Gln51* stop_gained 0.15
embB 4249732 c.3219C>G synonymous_variant 1.0
ethA 4326231 p.Asp415Tyr missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407995 p.Ser70Arg missense_variant 1.0