TB-Profiler result

Run: ERR2652950
Summary

Run ID: ERR2652950

Sample name:

Date: 31-03-2023 22:24:54

Number of reads: 580545

Percentage reads mapped: 99.68

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576255 p.Gly303Ala missense_variant 0.15
rpoC 766528 c.3160delC frameshift_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775935 p.Asp849Gly missense_variant 0.15
mmpL5 776982 c.1498delC frameshift_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781693 p.Pro45Leu missense_variant 0.12
fbiC 1304580 c.1650T>A synonymous_variant 0.15
Rv1258c 1407207 p.Ser45* stop_gained 0.17
Rv1258c 1407350 c.-10C>A upstream_gene_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834539 p.Val333Ala missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
katG 2153967 c.2145C>T synonymous_variant 0.15
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289554 c.-314delT upstream_gene_variant 0.12
kasA 2518135 c.21T>C synonymous_variant 0.1
thyA 3074489 c.-18G>A upstream_gene_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087007 p.Gln63Arg missense_variant 0.17
Rv3083 3448608 c.105G>A synonymous_variant 1.0
Rv3083 3449401 p.Val300Met missense_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474299 p.Asp98Gly missense_variant 0.12
whiB7 3568403 c.277T>A stop_lost&splice_region_variant 0.17
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
fbiB 3641806 p.Arg91His missense_variant 0.17
embC 4241940 c.2080dupA frameshift_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244032 p.Ile267Thr missense_variant 0.14
embA 4244082 p.Ala284Ser missense_variant 0.13
whiB6 4338461 p.Met21Val missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0