TB-Profiler result

Run: ERR2652956
Summary

Run ID: ERR2652956

Sample name:

Date: 31-03-2023 22:25:10

Number of reads: 822012

Percentage reads mapped: 99.76

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7265 c.2026T>A stop_lost&splice_region_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8933 c.1632G>A synonymous_variant 0.13
mshA 576287 p.Arg314Trp missense_variant 0.11
ccsA 620028 c.138G>A synonymous_variant 0.15
rpoB 761453 c.1647C>T synonymous_variant 0.12
mmpL5 777895 p.Gln196* stop_gained 0.13
fbiC 1303643 p.Pro238Leu missense_variant 1.0
fbiC 1304582 p.Asn551Ile missense_variant 0.15
Rv1258c 1407381 c.-41G>T upstream_gene_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476405 n.2748C>A non_coding_transcript_exon_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168281 p.Pro778Ser missense_variant 0.11
PPE35 2169133 p.Ala494Thr missense_variant 0.13
PPE35 2170793 c.-181A>T upstream_gene_variant 0.11
folC 2747453 c.145delC frameshift_variant 0.14
pepQ 2860164 c.255C>A synonymous_variant 0.13
thyA 3074329 p.Lys48Met missense_variant 0.12
ald 3086804 c.-16A>G upstream_gene_variant 0.1
fbiD 3339716 p.Gln200Arg missense_variant 0.11
Rv3083 3449832 c.1329T>C synonymous_variant 0.11
fprA 3474008 c.4_5dupCG frameshift_variant 0.18
fprA 3474080 p.Ala25Val missense_variant 0.12
fprA 3474573 c.567C>T synonymous_variant 0.13
panD 4044309 c.-28C>T upstream_gene_variant 0.12
embC 4240860 p.Leu333Arg missense_variant 1.0
embC 4241264 p.Gly468Ser missense_variant 0.11
aftB 4267922 c.915G>A synonymous_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0