TB-Profiler result

Run: ERR2652962
Summary

Run ID: ERR2652962

Sample name:

Date: 31-03-2023 22:25:16

Number of reads: 592566

Percentage reads mapped: 99.74

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5487 p.Gly83Asp missense_variant 0.13
gyrB 5739 p.Thr167Met missense_variant 0.11
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9814 p.Asn838Ser missense_variant 0.12
mshA 575424 p.Arg26His missense_variant 0.11
rpoB 762334 p.Gly843Asp missense_variant 0.13
rpoC 763917 p.Glu183Gly missense_variant 0.22
rpoC 766826 p.His1153Tyr missense_variant 0.12
mmpR5 779471 p.Thr161Ile missense_variant 0.12
rplC 801349 c.541T>C synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1673431 c.-771G>A upstream_gene_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102656 c.387C>T synonymous_variant 0.11
PPE35 2169722 c.891C>T synonymous_variant 0.14
pncA 2290211 c.-970G>A upstream_gene_variant 0.14
kasA 2518018 c.-97A>T upstream_gene_variant 0.11
kasA 2518331 c.218_219delGC frameshift_variant 0.14
kasA 2518697 p.Cys195Arg missense_variant 0.12
folC 2746834 c.764delC frameshift_variant 0.13
Rv2752c 3065955 p.Leu79Phe missense_variant 0.11
thyX 3067344 p.Ser201Asn missense_variant 0.17
fprA 3474327 c.321G>A synonymous_variant 0.11
fprA 3474751 p.Ile249Phe missense_variant 0.14
Rv3236c 3612515 p.Arg201His missense_variant 0.15
fbiB 3642178 c.646delG frameshift_variant 0.11
embC 4240860 p.Leu333Arg missense_variant 1.0
embA 4244337 c.1105C>T synonymous_variant 0.14
embA 4244407 p.Thr392Met missense_variant 0.13
embB 4247377 c.864G>A synonymous_variant 0.12
embB 4248353 p.Val614Leu missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0