TB-Profiler result

Run: ERR2652975
Summary

Run ID: ERR2652975

Sample name:

Date: 31-03-2023 22:25:37

Number of reads: 851862

Percentage reads mapped: 99.72

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576562 c.1215G>A synonymous_variant 0.11
rpoB 761537 c.1731C>G synonymous_variant 0.11
rpoC 766676 p.Asp1103Asn missense_variant 0.12
mmpL5 777743 c.736_737dupGG frameshift_variant 0.12
mmpR5 779069 p.Phe27Ser missense_variant 0.1
fbiC 1303643 p.Pro238Leu missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673537 p.Gln33Arg missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154296 p.Ala606Thr missense_variant 0.1
katG 2155608 c.504C>A synonymous_variant 0.11
PPE35 2168914 p.Pro567Ser missense_variant 0.17
Rv1979c 2223029 p.Phe46Leu missense_variant 0.13
pncA 2289530 c.-289T>C upstream_gene_variant 0.11
kasA 2519361 p.Tyr416Cys missense_variant 0.3
pepQ 2859466 p.Ala318Val missense_variant 0.14
Rv2752c 3064999 p.Gly398Glu missense_variant 0.11
Rv3083 3448664 p.Arg54Leu missense_variant 0.13
fprA 3474142 c.141delG frameshift_variant 0.12
fprA 3475112 p.Gly369Val missense_variant 0.12
fbiA 3640709 p.Leu56Gln missense_variant 0.14
fbiA 3641165 p.Ile208Thr missense_variant 0.14
fbiA 3641167 p.Ile209Val missense_variant 0.12
fbiA 3641315 c.774delG frameshift_variant 0.12
fbiB 3642641 c.1107G>A synonymous_variant 0.13
alr 3840232 p.Arg397Cys missense_variant 0.15
clpC1 4038179 c.2526C>T synonymous_variant 0.15
panD 4044351 c.-70T>C upstream_gene_variant 0.11
embC 4240860 p.Leu333Arg missense_variant 1.0
embA 4242619 c.-614C>T upstream_gene_variant 0.11
embC 4242710 p.Gln950Lys missense_variant 0.11
embA 4246208 c.2980delT frameshift_variant 0.11
embB 4246448 c.-66C>T upstream_gene_variant 0.12
embB 4247084 p.Asp191Asn missense_variant 0.11
embB 4247096 p.Pro195Ser missense_variant 0.12
embB 4248526 c.2018delT frameshift_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338654 c.-133A>G upstream_gene_variant 0.13
gid 4408240 c.-38A>G upstream_gene_variant 0.11